<p>Of the 571 adolescents that participated in the study, 355(62.2%) were female and the mean age was 15.96 years (SD=2.19). Of these, 46.6% (266/571), 95% CI: [42.5%-50.7%] of the respondents were psychosocially well during either or all of the COVID 19 lockdowns in Uganda. Older age adolescents residing in the central ward, and having a child during lock down were negative predictors of PSW. Whereas spiritual support from family members, favorable environment, having parents staying together during the lock down, spending time with friends and having time for oneself were positive predictors of psychosocial wellbeing. The coping strategies included speaking out their grievances, reporting any form of abuse done to them to any person who could help, getting what to do to avoid boredom at home, and learning to control their emotions during lockdown.</p>