<p>On 8 June 2022, Kayunga District Veterinary Department was notified of suspected African Swine Fever in Kangulumira Sub County, Kayunga District, Uganda. African swine fever is a highly contagious and fatal viral disease of both domestic and wild pigs. Mortality rate can reach 100%. We investigated to determine the scope of the outbreak, identify exposures for transmission and recommend evidence-based control and prevention measures.</p>