<p>A suspected case was acute onset of fever (&lt;37.5°C) and ≥2 of: headache, muscle or joint pain, unexpected bleeding, and any gastroenteritis symptom in a resident of Sembabule district from 1 November to 31 December 2020. A suspected animal case was livestock with any history of abortion. A confirmed case was a suspected case with laboratory confirmation by RT-PCR and/or enzyme-linked immunosorbent assay. We took blood samples from animals and herdsmen who worked with the index case for RVF testing and conducted interviews. We reviewed medical records and conducted active community search to identify additional suspects.</p>