<p>Rotavirus result in 2 million hospitalizations and 453,000 under-five deaths yearly prior to the global recommendation on the inclusion of rotavirus vaccine in national immunization programs, 95% of these deaths took place in low-income counties. The Rotavirus Surveillance System in Tanzania was launched in 2013, currently sentinel sites were nine with the aim of monitoring the impact of the vaccine on RV morbidity and mortality. We evaluated the performance of the system by assessing its attributes from 2020 to 2021.</p>