<p>We created blood donation clubs in the schools. The members of the blood donation clubs acted as champions to create blood donation awareness among other students in the school. We also created branded IEC materials, i.e. blogs, fact sheets and videos which were provided to the blood donation champions. These materials were used to create awareness regarding blood donation in the schools. We created a webpage on the Makerere University website to act as repository for all the study materials. The proportion of students who donated blood reduced from 23.4% in the baseline to 20.8% in the endline but this was not significant. Most respondents (77.19%, n=88) mentioned that they had donated from the school donation camps while others mentioned that they had donated from hospitals (22.81%, n=26), blood donation centers (14.04%, n=16) and regional blood banks (0.53%, n=12) at endline. The overall, the proportion of student who were knowledgeable about blood increased significantly from 28.3% at the baseline to 42.9% during the endline survey. The proportion of students with knowledge about blood donation significantly increased in the schools located in the urban area. Regarding the knowledge of the various aspects of blood donation, the proportion of students who were knowledgeable about the eligibility criteria for blood donation increased from 28.8% at baseline to 48.3% at the endline, those who were knowledgeable about the benefits of blood donation increased from 32.2% in the baseline to 41.3% in the endline and those who were knowledgeable about the potential beneficiaries of donated blood increased from 33% to 42.9%. All the chi square tests for the knowledge on the different aspect of blood donation were significant. The factors that were associated with blood donation include; current class [PR=1.37 (1.05, 1.79), p-value = 0.019) and access to internet [PR=1.61 (1.61, 2.24), p-value = 0.004).</p>