<p>Tuberculosis remains a major public health problem in Uganda despite implementing the WHO End TB Strategy (2016–2035), the Sustainable Development Goals (SDGs), and the Community Awareness Screening Testing and Treatment for TB (CAST TB) initiative. According to the national TB program, the target is to reduce the incidence of TB disease to 13/100,000 population by 2025. With three years left, we estimated the TB incidence by person, place, and time, Uganda, January-December, 2022.</p>