<p>The cross-sectional study was carried out between March and May 2022 at Kitete regional referral hospital in Tanzania. 246 HIV-infected adults were selected by systematic random sampling. Malaria was diagnosed using both Malaria Rapid Diagnostic Test (mRDT) and Malaria Microscopy. Social demographic data was collected using a structured questionnaire, while clinical history and laboratory parameters were extracted from patients' files. Data were analyzed using STATA version 15.1, and a p-Value &lt;0.05 was considered statistically significant. The study included consenting HIV+ adults, and excluded pregnant women and recent antimalarial users.</p>