<p>In 2022, we conducted a Quality Improvement Assessment among PLHIV in 7 priority sites in Eastern Rural Uganda. Sites were selected basing on a baseline threshold (1000&gt;TX_Curr) per site. The Six Sigma Methodology (Define, Measure, Analyze, Improve and Control) was used with the strategic objective to Improve VL Suppression Coverage from 63% to 95% for Non-suppressed Clients through continuous treatment monitoring interventions. Interventions included: • Home visits, telephone calls to improve on CD4 Tests, Viral Load Testing coverage and initiation on IAC. •Improved family based economic empowerment through the OVC Programme (CALHIV (0-17years). • Implemented the Modified CCLAD to improve adherence. • Improved data use through VL Line listing while triangulating primary data sources.</p>