<p>Rwanda reported its first SARS-CoV-2 confirmed case on March 14th 2020, and the first death was recorded in May 2020, with the period between June and October 2021 registering a spike nationally. To date, the overall recorded case fatality ratio is 0.01 (ref), and there is limited data discussing data describing factors associated with SARS-CoV-2 mortality at a sub-national level. The objectives of this were to identify, assess and discuss risk factors associated with SARS-CoV-2 mortality among patients admitted to Nyarugenge Treatment Centre.</p>