<p>A total of 618 suspected measles cases were recorded between 2018 to 2021, comprising 43.1% (266/618) females and 60.8% (375/618) children under five years, with no definite seasonality. Ho Municipality reported the highest number of suspected cases 13.2% (82/618), while Akatsi North District suspected the highest per population (31.4/100,000). Half of the cases reported to health facilities within three days of disease onset 50% (309/618) with 89.7% (547/610) of specimen collected within three days of facility visit. Among 381 cases with known vaccination status, 91% (346/381) had received at least one dose of measles-containing vaccine (MCV).</p>