<p>In South Africa, by 2030, 50% of type 2 diabetes mellitus (T2DM) patients, receiving treatment, must achieve optimal glycaemic control (HbA1c ≤7%). The Central Chronic Medicines Dispensing and Distribution (CCMDD) programme allows stable patients to collect their medication from community-based pick-up points. Information on glycaemic control for T2DM CCMDD-enrolled patients is scarce. We determined the proportion of T2DM CCMDD-enrolled patients with optimal glycaemic control at baseline and the rate and predictors of becoming sub-optimally controlled.</p>