<p>A total of 279 HBV cases were notified between January 2020-September 2022. The proportion of missing data was 285 (92.5%) for travel history, 230 (82.4%), for vaccination status, 230 (82.4%) for patient vital status, 245 (87.8%) for the onset of symptoms date, 230 (82.4%) for admission status and 36 (12.9%) for age variable. The HBV province prevalence was 6 cases/100 000 populations. More cases, 135 (48.4%) were from Gert Sibande district followed by Nkangala, 81 (30.1%), and lastly Ehlanzeni with 60 (21.5%) cases. The median age was 35 years (range 0-86 years).</p>