<p>Diarrhea is a main cause of morbidity and mortality in children under 5 responsible for approximately four billion cases and 1.1 million deaths annually. In developing countries, it causes two million deaths each year. The major causative organism responsible is Rotavirus which is responsible for one-third of hospitalizations with approximately 40% mortality. Globally, rotavirus is the most frequent cause of severe acute gastroenteritis (AGE) /acute watery diarrhea among young children.</p>