<p>Forty-six suspected measles cases were identified in four villages in DSA, of which 58.7% (27/46) were females. Median age was 14 months (range=11-54). Overall case fatality rate (CFR) was 33% (4/46). Sex-specific CFR was 22.2% (6/27) for females. Place-specific CFR was highest in Misside Busra 50% (2/4). Test positivity rate was 65% (26/40). Mortalities occurred between March 16th and 19th 2022 before outbreak investigation commenced. Only 8.7% (4/46) of affected children had received measles vaccination. Rash, fever and cough were symptoms reported among all suspected cases.</p>