<p>The WHO estimates that Neonatal infections that include sepsis result in over 550,000 neonatal deaths every year. In preterm infants, sepsis is one of the major cause of neonatal deaths worldwide as well in Rwanda. Neonatal sepsis is subcategorized into early onset (EOS) and late onset (LOS) depending on the time of onset. Following increase in number of neonatal infections at Nyamata Hospital in December 2023, we conducted a study to characterize neonatal sepsis infections in Nyamata Hospital.</p>