<p>We conducted an analytical cross-sectional study among 384 AGYW. Participants were randomly selected proportionate to number initiated on PrEP in 20 health facilities in Mazowe District. Using Interviewer-administered questionnaires data was collected on sexual behaviour, reasons for starting PrEP and determinants of self-discontinuation. We performed logistic regression analysis to determine independent factors for PrEP self-discontinuation.</p>