<p>Antigen and molecular-based testing for COVID-19 is suboptimal in Nigeria. Self-testing has been a useful strategy to expand COVID 19 testing in developed countries, however in Nigeria, self-testing has not been implemented. To expand COVID-19 testing, we implemented a novel COVID-19 self-testing pilot project in Akwa Ibom and Nasarawa States, to inform scaling-up to other states.</p>