<p>Public health surveillance is the ongoing systematic collection, analysis, and interpretation of health-related data essential to the planning, implementation, and evaluation of public health practice. Malaria is parts of weekly reportable disease and has a public health importance in the district of Tahtay koraro. Therefore, the current system evaluation is aiming to assess the performance of core activities of surveillance system and determine how system operates to meet its stated purpose and objectives, by considering Malaria disease in Tahtay koraro district, Northwest zone, Tigray regional state, 2022.</p>