<p>In Ethiopia, the national PHEOC which has a room covering 40 square meters was established and equipped with physical and ICT infrastructure. It’s a multi-purpose space that is expandable accordingly depending on the situation of the incident. The public health emergency operation center expanded to all regions and priority eight (8) subregional sites of Ethiopia. In 2017, PHEOC was first activated to coordinate the Acute Water Diarrhea disease outbreak that happened in Ethiopia, Since then it has been activated to coordinate different public health emergency responses. In addition to the real public health emergency response, different simulation exercises, and tabletop exercises with public health emergency management officers and other multisector partners to test the PHEOC procedures and plans were conducted at the national level.</p>