<p>Tetanus is a vaccine preventable disease caused by Clostridium tetani bacterium. In 2019, 54% of Angolan women of reproductive age received at least two doses of tetanus toxoid-containing vaccine. Neonatal tetanus remain a public health concern, in regions with low immunization coverage and restricted access to clean delivery. Without medical care intervention case-fatality rate from the diseases can be as high as 100%. In this case report, we describe the epidemiological and clinical presentation of a neonatal tetanus case treated at Engela district hospital to identify the source of infection and inform preventive in the region.</p>