<p>The mortality trend in Tanzania was seen to decrease with time from 2018 to 2020. Most deaths occurred among male patients, patients with advanced diseases (WHO stage 3 and 4), TB coinfection, CD4 count &lt;200 cells/µl, and those with malnutrition. This mortality would be further reduced by improving TB screening and treatment, nutritional support, and promoting early diagnosis and treatment of HIV infection.</p>