The UNAIDS has set a target of ending HIV/AIDS as a public health threat by 2025. In 2021 alone, about 84 million people were infected with the disease globally. HIV/AIDS prevalence in Ghana was 2.0% in 2021, with regional variations. It is therefore crucial to analyse HIV/AIDS surveillance data to help gather credible information for decision making. This study analysed the HIV/AIDS Surveillance data to assess its quality and determine the distribution of cases.