TB is one of the top 10 causes of death globally and the leading cause from a single infectious agent, ranking above HIV/AIDS. Ethiopia is among the 30 high TB and TB/HIV burden countries globally with an estimated TB incidence rate of 140/100,000 populations. The purpose of this study is to describe Trends of Tuberculosis Case Detection Rate and treatment outcomes from 2017 to 2021 in Oromia zone, Amhara RegionTB is one of the top 10 causes of death globally and the leading cause from a single infectious agent, ranking above HIV/AIDS. Ethiopia is among the 30 high TB and TB/HIV burden countries globally with an estimated TB incidence rate of 140/100,000 populations. The purpose of this study is to describe Trends of Tuberculosis Case Detection Rate and treatment outcomes from 2017 to 2021 in Oromia zone, Amhara Region