Cross-sectional study, from February to July 2020. Collected approximately 5g of rectal feces and MLN from 140 pigs at slaughter. E. coli and Salmonella spp isolates were identified by colony morphology and confirmed by biochemical testing. Using the Kirby-Bauer disk diffusion method, we tested the susceptibility of the isolates against 10 antibiotics. Multi-drug resistance (MDR) was defined as any isolate resistant to three or more antimicrobial classes.  We observed slaughter practices and environmental hygiene. Data collected was summarized descriptively. 