Leprosy is a chronic disease caused by Mycobacterium leprae transmitted through the airways by prolonged exposure with an infected person without treatment. Every year more than 200,000 new cases are reported worldwide, mainly in Africa, Southeast Asia and Latin America. In Mozambique, leprosy is an endemic and re-emerging disease and is one of the most prevalent neglected tropical diseases in several provinces, particularly Zambézia, Nampula and Cabo Delgado. In this study, we evaluated the leprosy surveillance system in Mozambique for the period 2011 to 2020. 