A total of 9,503 suspected typhoid fever cases were detected of which 37.5% (3,564/9,503) were tested and 57.8% (2,060/3,564) were positive. Females were 69.5% (1,431/2,060). The median age of confirmed cases was 26 years (Range: 1–92 years). The overall prevalence was 264/100,000 population with 2020 recording the highest prevalence of 465/100,000 population. Persons 30–49 years had the highest age-group prevalence (1866/100,000 population). Gambaga recorded the highest sub-district prevalence  611/100,000 population. The highest monthly proportion of cases 15.3% (1,449/9,503) was recorded in August, peak of rainy season each year.