We collected descriptive data on all AGYW 10-24 years who obtained SGBV health services at ten high-volume health facilities from March 2020 to December 2021, the main COVID-19 period in Uganda. We conducted a case-control study among these AGYW. A case was ≥1 SGBV episode experienced by an AGYW aged 10-24 years residing in Tororo and Busia Districts. For every case, we identified two neighbourhood-matched AGYW controls that reported no SGBV. We interviewed 108 randomly-selected cases from health facility line lists and 216 controls on socio-demographics, socio-economics, and SGBV experiences during COVID-19. We conducted logistic regression to obtain adjusted odds ratios and confidence intervals.