Evey year, around 1.3 to 4 million people in the world suffer from cholera and 21,000 to 143,000 die from it. In Rwanda, especially in the Kivu Lake belt, cholera remains a public health concern. Cholera suspects cases were reported beginning 20th February, 2023 from three sectors of Nyamasheke District: Mahembe, Kagano and Gihombo, each bordering lake Kivu. An investigation was conducted with the aim to confirm diagnosis and propose interventions.