A total of 8,502 cases were recorded from the year 2020 to 2021. The incidence rate over the period was 1129 cases per 10,000 population with a case fatality rate of 0.53% (45/8,502). The incidence for the year 2020 was 812.4 cases per 10,000 population. Higher proportion 57.3% (2,252/3,931) of cases were among age group 25 to 44 years. The majority of cases were recorded among males 59.7% (4,667/8,502). Trends revealed high incidence of cases in the 1st and 2nd quarters of the year with peaks following festive seasons. More than two-thirds (76.8%) of cases were inhabitants of the Ayawaso West Municipality.