From January to November 2022, 133 suspected cases were identified and investigated; with the highest proportion aged 0-5 years (32.3%), male (54.9%), rural residence 62.4%, family members as contacts 49.2% and Isu LGA (16.2%) as highest recorded cases. There were 37 laboratory-confirmed cases including the index case and 1 death with a case fatality rate of 2.7%. All 37 cases experienced fever, rashes on the face, rashes on the palm of the hand, rashes on the soles of the feet, pustules.