Unmatched case–control study was conducted in Raya-Kobo district from November 14 to December 8/2022. Sample size was determined by using, Epi-infoTM7 from previous study conducted at Basoliben, 90 participants (30 cases and 60 controls) were included in the study. A face-to-face interview by using structured questionnaire was used to collect the data. Cases were found by home-to-home searching and controls were selected from neighbors of cases. Cases were any person who developed fever with maculopapular rash and one of cough, coryza or conjunctivitis while controls were without such diagnosis. Data were cleaned, entered and analyzed by using SPSS-26. In the multivariable logistic regression analysis factors with P-value &amp;lt;0.05 was declared statistical significance. Binary and multivariate logistic regression analysis was conducted to identify risk factors associated with measles outbreak at a p-value ≤0.05.