We found 2,236 suspected scabies cases in Hoima district. Rwentale Village had the highest attack rate (AR=233/1,000 population) among area villages. Children aged 5-14 years were more affected (AR=64/1,000) than persons aged ≥15 years (AR=8/1,000) (p&amp;lt;0.0001). Males (AR=22/1,000) were as affected as females (AR=20/1,000) (p=0.76). Rwentale Village includes a fishing area known as Rwentale Landing Site where 1,119 (50%) cases in Hoima district were identified. At this landing site, cases began in April, shortly after the end of the peak fishing and trading season. Being aged 5-14 years (AOR=4.9, 95%CI 2.0-12), being male (AOR=2.4, 95%CI 1.1-5.1), living with another case (AOR=3.1, 95%CI 1.5-6.2), and sharing personal items with persons infested with scabies (towel, beddings, clothes, or sponges) (AOR=8.9, 95%CI 2.2-36) were associated with case status.