Facility-based Crossectional study design with record review was used to identify the magnitude and risk factors of death in Covid-19 in Tigray, Ethiopia.The entire database of Covid-19 patients admitted to all treatment facilities in the Tigray region in 2020 served as the study population. The entire Covid-19 patient group up until October 19, 2020 served as the study's sample population.  Data on the mortality of COVID-19 cases were retrieved using a data extraction technique from registers, patient cards, and patient line lists. Data were entered in EpiData, and analyzed using SPSS 21. Odds ratios with 95% Confdence Intervals were estimated and the level of signifcance was declared at p-value≤0.05.