<p>Hepatitis B (HBV) and C (HCV) are a public health problem, particularly in low- and middle-income countries. In Mali, West Africa, few data exist on the prevalence of co-infections with these hepatitis and Human Immunodeficiency Virus (HIV) among vulnerable groups such as female sex workers (FSWs). This cross-sectional study conducted in Bamako, main city of Mali, among 400 FSWs (200 HIV+ and 200 HIV-) aimed to determine the prevalence and factors associated with HBs antigen on one hand and HCV antibodies on the other.</p>