<p>Overall, 142 confirmed cases of Sudan virus disease (SVD) were reported, of which 55 died (CFR: 39%), and 87 recovered. In addition, 22 deaths among probable cases were reported in individuals who died before samples could be taken (overall CFR: 47%). Overall, nine Ugandan districts were affected by this outbreak: Bunyangabu, Jinja, Kagadi, Kampala, Kassanda, Kyegegwa, Masaka, Mubende, and Wakiso. When the number of permutation test was set to 9999, Moran’s I = 0.37261, P = 0.0085, and was significant at significance level of 0.01. Spatial cluster analysis identified two most likely cluster; one large multi-centered cluster in districts of Mubende and Kassanda with 13 locations and one cluster in Rubaga division in Kampala district.</p>