<p>After the establishment of the Mbale REOC, complete daily regional surveillance reporting increased from 43% to 93%. Over 12 months, the REOC conducted on average 15 partner coordination meetings. The REOC supported 16 districts with logistics and inventory management including coordination of material supply transfer between districts. The REOC provided training in laboratory outbreak monitoring and evaluation to 21 regional trainers, 72 district mentors, and 256 facilities. The REOC established a mobile laboratory in the region that reduced COVID-19 PCR sample result turnaround time from ≥7 to ≤2 days, and increased the number of tested samples from 200 to 500 per day.</p>