<p>A hospital-based cross-sectional study was conducted at Jinja Regional Referral Hospital among 297 adult patients in care. These were selected by systematic, purposive and convenience sampling methods. Quantitative and qualitative approaches of data collection and analysis were employed. Data analysis was done using a statistical software package (SPSS-16). Prevalence Ratios (PRs) were used to report the association between non-adherence to diabetes treatment and the independent factors.</p>