<p>Summary : Introduction: Rabies remains a serious public health problem that compromises the success of treatment with the complete rabies vaccine. The steady increase in incidence with the demand for comprehensive anti-rabies post-exposure prophylaxis (PEP) against rabies. Rabies occurs when complete rabies vaccines are not used in animal bites. Objective: To study the factors associated with comprehensive rabies post-exposure prophylaxis of animal bite cases in Guinea-Bissau</p>