<p>We analyzed PrEP and HIV testing data from HIV testing registers and DHIS2 from October-December 2021 at the four sites to determine baseline numbers of AGYW aged 15-24 years who tested HIV negative, were screened, eligible for, and initiated on PrEP. Screening rate was the proportion of HIV-negative AGYW screened for PrEP eligibility; uptake was the proportion of PrEP-eligible AGYW started on PrEP. Our QI team conducted focus group discussions with healthcare workers (HCW) and AGYW peers to identify and develop interventions for root causes of poor PrEP uptake, and measured changes in screening and eligibility rates.</p>