<p>We conducted a cross-sectional survey among healthcare workers, from 10 to 13 January 2023, at Kingharman Road Hospital in Freetown, Sierra Leone. A structured pre-tested questionnaire was used to collect data on needle-stick and sharp-related injuries from healthcare workers. Multiple logistic regression was used to report the adjusted odds ratio (aOR) and the 95% confidence interval (CI) to identify factors associated with needlestick and sharp-related injuries.</p>