<p>Results from 2021 suggest the quality of SARS-CoV-2 testing increased during 2021 and that the results obtained by these laboratories met the quality criteria established by international standards. Compared to the 2021 program, the 2022 program faced more challenges, with most laboratories having stock-outs of reagents and ceasing SARS-CoV-2 testing altogether, explaining the decline of submissions and testing quality.</p>