<p>The outbreak of COVID-19 posed significant threats to international health. Students in tertiary institutions are generally susceptible to the virus. Vaccines remain one of the key public health strategies for the prevention and control of infections. However, the success of the COVID-19 vaccination program will depend on people’s attitudes toward the vaccine. We, therefore, explored the factors associated with vaccine hesitancy among selected students of the college of health sciences and technology in Ijero-Ekiti, Southwestern part of Nigeria.</p>