<p>A total of 3,573 suspected measles cases and 38 (1.1%) deaths were reported between January and December 2022. Cases peaked in November and December and covered all the 10 states and 3 administrative areas. Of the reported cases, 2,453 (68%) were epi-linked, 369 (10.3%) laboratory confirmed, 85 (2.4%) clinically compatible, and 519 (14.5%) discarded. Majority of the cases were reported from Central Equatoria State 946 (26.5%). The highest attack rate was 57.6 per 100,000 population in Unity state. Children under five years were most affected with a cumulative attack rate of 89.6 cases per 100,000 population. Only 173 (4.8%) of the confirmed, epi-linked, and clinically compatible cases were vaccinated.</p>