<p>Monkeypox is a global public health problem. In West Africa more than 35 cases have been reported to WHO. On July 30, 2022, the health district of Tabou was informed by the detection of a suspected case of monkeypox in Iboké, a health area bordering Liberia, a country to which a confirmed case of monkeypox was reported. An investigation was carried out with the aim of describing the case, searching for other cases and proposing prevention and control measures.</p>