<p>Studies on Antiretroviral therapy programs in Africa have shown a significant reduction of mortality among HIV clients. Mortality trend among HIV clients on Antiretroviral therapy (ART) in Tanzania from 2018 to 2020 and factors associated with it are poorly described. The aim of this study was to assess the mortality trends and to identify predictors of mortality in HIV-infected patients on ant-retroviral therapy in 26 regions in Tanzania mainland</p>