<p>Study findings revealed that: 64% of the identified NCs were against the technical ISO 15189:2012 requirement compared to 33% against the management requirement (n=261). Most NCs occurred in the testing-phase (77%) compared to 20% and 3% in pre-testing and post-testing phases respectively (n=261). Across the twenty-five clauses of ISO 15189:2012, 20% (n=261) NCs were identified against clause 5.6 about ensuring quality of examination. Regarding experiences of laboratory personnel, most of them indicated that it was motivating to be working in an internationally accredited laboratory. However, expressed to have experienced more fatigue and pressure arising from increase in responsibilities associated with accreditation works. Most challenges encountered by the laboratories during accreditation journey included inadequate human resources, limited funding, facilities' limited management commitment towards accreditation and complexity of the identified NCs.</p>