<p>Of the 384 AGYW, 57.8% were married, 24.5% were divorced and 17.7% had never married. Reasons for starting PrEP among AGYW were multiple sexual partners (29.2%) and promiscuous sexual partner (29.2%). Prevalence of PrEP self-discontinuation was 41% with a median time to self-discontinuation of 4 (IQR 2-5) months. Of 157 AGYW who self-discontinued PrEP, 59.2% had multiple sexual partners and 57.3% had transactional sex in the preceding 6 months. Independent factors associated with PrEP self-discontinuation among AGYW were being a sex worker [aOR 4.86; 95% CI (1.33-17.69)], non-disclosure of PrEP status to sexual partner [aOR 3.63; 95% CI (2.13-6.19)], being discouraged to take PrEP by sexual partner [aOR 3.04; 95% CI (1.31-7.04)] and experiencing PrEP side effects [aOR 2.38; 95% CI (1.49-3.81)].</p>