<p><strong>Background:</strong> Chronic kidney disease is a condition where high blood glucose or blood pressure damages the blood vessels in the kidneys and reduces their function. Chronic kidney disease can be prevented by controlling blood glucose and blood pressure, avoiding harmful medications, and changing lifestyle. Though prior studies were conducted on chronic kidney disease among adult diabetics in the Amhara region, possible determinant such as glycated hemoglobin level was not assessed.The study objective was to identify the determinants of Chronic Kidney Disease Among Adult Diabetic Patients at Dessie Comprehensive Specialized Hospital, Amhara Region, Ethiopia,2024.</p>