<p><strong>Result:</strong> A total of 149,560 malaria cases were reported from January 2019 to December 2023 in Kaffa zone. Of these, 144,296(96.5%) diagnosed parasitological and 5264(3.5%) clinically. Among the confirmed cases <em>Plasmodium falciparum</em> accounted for 87,716(61%) and <em>Plasmodium vivax</em> shared 56,580(39%). Across districts case distribution varies from 17-384/10,000 population. The annual parasite incidence increased from 5.1/1000 in 2019 to 6/1000 in 2020, 8.94/1000 in 2021, 25.29/1000 in 2022 and 71.3/1000 in 2023. Malaria transmission in the zone reached to its maximum peak during summer (July-Aug) season and followed by spring (Sep-Nov) season. The zonal malaria case fatality rate was 41/100,000cases.&nbsp;</p>