<p>&nbsp;<strong>Methods</strong>: A community-based case-control study was conducted. This Investigation was conducted in Lare district which is located 775 Km away from Addis Ababa and 31 km away from Harare town Oromia region. <strong>Cases: </strong>any person who is residing in Kuergeng town in Lare districts with fever and maculopapular generalized body rash and develops any of the following symptoms; Cough, Coryza, or Conjunctivitis between. <strong>Controls: -</strong> any person residing in the same community with a case who did not develop signs and symptoms of measles. All the identified cases of measles by line list and active case search in Kuergeng town and controls who are neighbors for case patients were recruited. A semi-structured questionnaire was used to collect available data. Data was coded, organized, and entered into Epi Info version 7.2.2 and exported to SPSS version 27 for analysis. Logistic regression analysis was used to identify determinants of measles infection.&nbsp;</p>