<p>&nbsp;</p><p><strong>Result:</strong> A total of 350 cases of rubella were identified from November 26, 2023, to March 19, 2024, in Adigrat town. The median age of the cases was 7 years (interquartile range=4.5-10). The attack rate was high in children aged five to nine years (11/1000), and in kebelle 04 (8/1000). Five out of seven samples were tested positive for rubella-specific IgM antibodies. Having school contact (Adjusted odds Ratio=6.302:95%CI= 2.981-13.322), household contact (AOR=6.032: 95% CI=2.393-15.209), and five and above family size (AOR=2.669: 95% CI =1.28-5.562) were significantly associated with rubella infection.&nbsp;</p>