<p><strong>Conclusions:</strong> MCV2 coverage in Durame town, while improving, is still below the WHO target of ≥ 95%. Factors influencing vaccination rates include maternal education, awareness of vaccine-preventable diseases, and knowledge of the two-dose requirement. Barriers include a lack of information, general unawareness, and fear of vaccine side effects. To improve MCV2 coverage, efforts should focus on increasing awareness, educating mothers, and improving access to health services.</p>