<p><strong>Background</strong>: Cholera is an acute watery diarrheal disease caused by a bacteria called Vibrio cholerae. It is transmitted by fecal-oral route. It is a global public health threat. If left untreated, the fatality rate can range from 35% to 50%. However, with prompt treatment it is below 1%. A single confirmed case is enough to declare the outbreak. Cholera is a challenge in Bahir Dar Zuria district. However, the risk factors were not understood. Therefore, the aim of this study was to identify risk factors and control the outbreak.</p>