<p><strong>Background: </strong>Malaria is a life-threatening parasitic infection caused by <em>plasmodium</em> specious. Several strategies and programs were developed and implemented to control and eliminate malaria at global and national level. Ongoing surveillance data analysis is required to monitor and evaluate the intervention measures; that helps to achieve national malaria elimination target. The study was aimed to assess trend and distribution of malaria cases by person, place and time in Kaffa zone.&nbsp;</p>