<p><strong>Background: </strong>Tuberculosis (TB) remains a major public health concern, with early detection being critical for effective treatment and control. The tuberculosis case detection rate measures the percentage of newly detected TB cases, including relapses, against the estimated number of cases in a given area. This study was aimed to assesses the Tuberculosis case detection rate in different clusters, highlighting variations and the distribution of pulmonary and extra-pulmonary tuberculosis cases in Dangila District, Northwest Ethiopia 2022.&nbsp;</p>