<p>Background: Rabies is a deadly zoonotic disease that remains a major public health concern in Ethiopia.&nbsp;<br>This study aimed to assess the knowledge, attitude, and practices toward rabies prevention and control,&nbsp;<br>and identify associated factors among dog owners in Chiro, West Hararghe, Ethiopia.<br>Methods: A community-based cross-sectional study was conducted among 326 randomly selected dog-<br>owning households. Data on socio-demographic characteristics, knowledge, attitude, practices, and&nbsp;<br>personal/health-related factors were collected using a structured questionnaire. Bivariate and multivariable&nbsp;<br>logistic regression were used to identify factors associated with good rabies prevention and control&nbsp;<br>practices.</p>