<p>A 1:2 unmatched case-control study was conducted in Godere district from December 4 to 31, 2021. We had enrolled 92 cases and 184 controls. Cases were individuals with malaria signs and symptoms with laboratory confirmation, while controls did not exhibit any such symptoms. To gather data, a semi-structured questionnaire was utilized. Variables associated with malaria infection were identified using bivariate and multivariate binary logistic regression model. Odds ratio along with 95% CI was computed to identify determinants of malaria outbreak. A p-value of less than 0.05, an acceptable level of statistical significance, was defined.&nbsp;</p>