<p>Robust cholera prevention, control, and elimination programs have been implemented in Ethiopia. Strong commitment towards a multi-sectorial approach for eliminating cholera was conducted by developing a Multi-Sectoral Cholera Elimination Plan aligned with the HSTP-II, NAPHS, and One WASH Plan. Additionally, hotspot analysis and OCV administration were conducted. Even though the effort, low access of safe water, constrained availability of critical cholera supplies, insufficient OCV stocks, exhausted cholera response capacities, and inadequate financial were the identified gaps. The emerging challenges that might be contrary to the progress of ending cholera were climate change, conflict, political instability, population displacements&nbsp;</p>