<p>&nbsp;A facility based comparative cross-sectional study was conducted among public and private health facilities in Afar region from May 4th to 26th<strong>,</strong> 2023. A total of 334 healthcare providers’ and patient charts were recruited with multistage sampling technique. Data were collected using pre-tested and structured questionnaire, entered to Epi-data 3.1 and analyzed with SPSS version 25.0. Binary logistic regression analysis were applied to assess factors associated with guideline adherence at p-value &lt;0.05.&nbsp;</p>