<p>Malaria is a major public health problem in sub-Saharan Africa including Ethiopia. Malaria epidemics is a serious public health emergency in Ethiopia due to its unstable transmission. On April 10, 2024, Fadis district Health Office reported that the district was experiencing an unusually high number of cases of malaria in five kebeles. We conducted the investigation to verify the existence of the outbreak, to identify the risk factors for transmission of malaria and to undertake appropriate prevention and control interventions.</p>