<p><strong>Results</strong>: Out of the respondents, 271 (64.4%) adhered to lifestyle practices. Knowledge about lifestyle modifications (AOR = 4.48, 95% CI: 2.30–8.75), good self-efficacy (AOR = 2.84, 95% CI: 1.61–5.01), good adherence to antihypertensive medication (AOR = 4.64, 95% CI: 2.54–8.45), education (AOR = 0.40, 95% CI: 0.18–0.89), and being overweight/obese (AOR = 0.07, 95% CI: 0.04–0.14) were key determinants of adherence.&nbsp;</p>